{"id":3337,"date":"2023-08-11T15:55:36","date_gmt":"2023-08-11T13:55:36","guid":{"rendered":"https:\/\/dermaclub.it\/basal-cell-carcinoma-basal-cell-epithelioma\/"},"modified":"2024-11-15T13:47:02","modified_gmt":"2024-11-15T12:47:02","slug":"basal-cell-carcinoma-basal-cell-epithelioma","status":"publish","type":"post","link":"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/","title":{"rendered":"Basal cell carcinoma (basal cell epithelioma)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]Basal cell carcinoma (previously basal cell epithelioma) is the most common cancer for humans. There are an estimated 150,000 new cases each year in Italy, while in the United States, over 3.6 million cases are diagnosed annually. The number of basal cell carcinoma cases is increasing faster than any other tumor. It is a cancer that affects the skin and takes its name from the fact that the cells that degenerate are those located in the basal layer of the epidermis (the basal cells). Unlike other tumors, basal cell carcinoma has little or no tendency to spread by metastasis. Despite this, it is important to understand that it is in no way a benign tumor. In fact, it is difficult to eradicate in five to ten per cent of cases, and has a tendency to recur, as well as invading and destroying nearby tissues including muscles, cartilage and bone. As with most cancers, the early diagnosis and early treatment of basal cell carcinoma is the best weapon available.<br \/>\n &gt;  1.000.000). E\u2019 un processo tumorale che interessa la cute e prende il nome dal fatto che le cellule che degenerano sono quelle situate nello strato basale dell\u2019epidermide quindi denominate Cellule Basali. Il Carcinoma Basocellulare o Epitelioma Basocellulare \u00e8 anche il tumore umano con il pi\u00f9 alto tasso di incremento per anno. A differenza di altri tumori, questo ha poca o nulla tendenza a diffondersi per metastasi; questo fatto non deve far pensare che si tratti di un tumore cosiddetto \u201cbenigno\u201d. Infatti nel 5-10% dei casi \u00e8 di difficile eradicazione, tende a recidivare e ad invadere e distruggere i tessuti vicini compreso i muscoli le cartilagini e l\u2019osso.<br \/>\nCome per la maggioranza dei tumori anche per il Carcinoma Basocellulare o Epitelioma Basocellulare la diagnosi precoce ed il trattamento precoce \u00e8 la miglior arma a disposizione della medicina.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Indice<\/p>\n<span class=\"ez-toc-title-toggle\"><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Causes\" >Causes<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#People_at_risk\" >People at risk<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Warning_signs\" >Warning signs<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Dermatological_assessment\" >Dermatological assessment<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Clinical_forms_of_basal_cell_carcinoma\" >Clinical forms of basal cell carcinoma<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Nodular_form\" >Nodular form<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Confusion_with_moles\" >Confusion with moles<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Basal_cell_carcinoma_treatment_options\" >Basal cell carcinoma: treatment options<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Surgery\" >Surgery<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Thermal_destruction\" >Thermal destruction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Mechanical_destruction\" >Mechanical destruction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Destruction_with_x-rays_ionizing_rays\" >Destruction with x-rays (ionizing rays)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Treatment_with_topical_pharmaceuticals\" >Treatment with topical pharmaceuticals<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Photodynamic_therapy_PDT_protocols_for_basal_cell_carcinoma\" >Photodynamic therapy (PDT): protocols for basal cell carcinoma<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Treatment_with_topical_pharmaceuticals-2\" >Treatment with topical pharmaceuticals<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/dermaclub.it\/en\/skin-diseases\/basal-cell-carcinoma-basal-cell-epithelioma\/#Examples_of_PDT_treatment\" >Examples of PDT treatment<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Causes\"><\/span><strong>Causes<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]In 90% of cases, basal cell carcinoma is caused by the excessive exposure to the sun or ultraviolet (UV) lamps.<br \/>\nIndeed, in nine out of ten cases, basal cell carcinoma appears on the areas of skin most exposed to UV light, such as the face, hairline for bald people, ears, shoulders, and back.<br \/>\nIn the remaining 10% of cases, the causes of basal cell carcinoma are linked to genetics (familial form), or the use of drug treatments such as immunosuppressants (organ transplants), cortisone (chronic inflammatory or autoimmune diseases) or chemotherapy (neoplasms). X-ray treatments (radiotherapy, cobalt therapy) may also induce basal cell carcinoma.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"People_at_risk\"><\/span><strong>People at risk<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]For cases of basal cell carcinoma caused by UV rays, individuals who are particularly at risk are those who:<\/p>\n<ul>\n<li>are sensitive to UV rays. This often applies to individuals with fair skin, blond hair, and blue eyes, or those with freckles and red\/copper hair; <\/li>\n<li>engage in outdoor activities;<\/li>\n<li>spend or have spent long periods in tropical or equatorial areas, and<\/li>\n<li>use artificial tanning methods with UV rays<\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Warning_signs\"><\/span><strong>Warning signs<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]For early diagnosis and more effective treatment, it is important to know the warning signs of basal cell carcinoma.<br \/>\nThese are:[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<ul>\n<li>A lesion appears where the skin peels off and bleeds. Scabs form, which then peel off and reform again and again.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_single_image image=&#8221;431&#8243; img_size=&#8221;300X200&#8243; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<ul>\n<li>An inflammatory plaque with no apparent cause appears and slowly expands<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_single_image image=&#8221;430&#8243; img_size=&#8221;large&#8221; alignment=&#8221;center&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<\/p>\n<ul>\n<li>A flesh-colored or reddened nodule forms<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_single_image image=&#8221;428&#8243; img_size=&#8221;300X250&#8243; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<\/p>\n<ul>\n<li>A round erosion appears where the skin does not reform<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_single_image image=&#8221;435&#8243; img_size=&#8221;300X250&#8243; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<\/p>\n<ul>\n<li>An area resembling a scar that was not caused by any trauma or injury appears<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_single_image image=&#8221;433&#8243; img_size=&#8221;300X250&#8243; alignment=&#8221;center&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Dermatological_assessment\"><\/span><strong>Dermatological assessment<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;432&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]caratteristiche del tumore. A dermatologist usually has no difficulty in diagnosing basal cell carcinoma from the clinical appearance alone.<br \/>\nIn more difficult cases, a dermatologist may use a dermoscopic examination which uses a magnifying instrument on the lesion, the results of which can be assessed for the characteristics of the tumor.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;3\/4&#8243;][vc_column_text]In cases where the clinical and dermatoscopic diagnosis is critical, a histological examination is performed after taking a sample of the skin lesion under local anesthesia.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;429&#8243;][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Clinical_forms_of_basal_cell_carcinoma\"><\/span><strong>Clinical forms of basal cell carcinoma<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]There are many clinical forms of basal cell carcinoma.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Nodular_form\"><\/span><b>Nodular form<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;440&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<span style=\"font-weight: 400;\">A nodule appears that tends to slowly increase in size.<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">In the second stage, the nodule will ulcerate and bleed.<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Confusion_with_moles\"><\/span><b>Confusion with moles<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]Many moles may be nodular, especially those on the face, and this can sometimes cause confusion with the nodular basal cell carcinoma.<br \/>\n However, the salient difference is that the mole will have been present for many years, unlike basal cell carcinoma nodules, which will have appeared recently.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<b>Miescher&#8217;s nevus (MN) of the face<\/b>[\/vc_column_text][vc_single_image image=&#8221;434&#8243; img_size=&#8221;300X270&#8243; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<b>Nodular basal cell carcinoma<\/b>[\/vc_column_text][vc_single_image image=&#8221;436&#8243; img_size=&#8221;300X270&#8243; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<b>Ulcerated basal cell carcinoma next to a nevus of Miescher<\/b>[\/vc_column_text][vc_single_image image=&#8221;437&#8243; img_size=&#8221;300X270&#8243; alignment=&#8221;center&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Basal_cell_carcinoma_treatment_options\"><\/span><strong>Basal cell carcinoma: treatment options<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]Although a rarely metastasizing and therefore relatively benign tumor, basal cell carcinoma has a surprising ability to reappear after treatment. One reason for this behavior is that basal cell carcinoma does not have defined margins, and nests of tumor cells can be found even at some distance from the identified tumor core. Another reason is that the skin where the basal cell carcinoma tumor appears is already sufficiently damaged to reproduce another one, either in the immediate or distant future. The earlier a basal cell carcinoma tumor is identified and the earlier action is taken, the higher the chances of therapeutic success.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Surgery\"><\/span><strong>Surgery<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]Surgery is still the standard treatment of choice today.<br \/>\nIt is performed under local anesthesia and removes the tumor with a portion of apparently healthy tissue around it.<br \/>\nHowever, the downsides of surgery are the often high cost, likelihood of tumor recurrence and evident scarring which may cause aesthetic discomfort.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Thermal_destruction\"><\/span><strong>Thermal destruction<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]Basal cell carcinoma can be destroyed by either hot or cold thermal waves that are generated through treatment techniques such as radiofrequency, laser therapy or liquid nitrogen, etc.<br \/>\nHowever, thermal destruction has many drawbacks such as scarring, damage to healthy tissue, possibility of infection of the treated area, and the recurrence of the tumor.<br \/>\nFor these reasons, thermal destruction has been replaced by more viable techniques.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Mechanical_destruction\"><\/span><b>Mechanical destruction<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]Basal cell carcinoma can also be removed mechanically with a sharp spoon (curette) that enucleates the tumor tissue from healthy tissue.<br \/>\nMechanical destruction or curettage has drawbacks such as scarring and the possibility of the tumor recurring.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Destruction_with_x-rays_ionizing_rays\"><\/span><b>Destruction with x-rays (ionizing rays)<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]Destruction of basal cell carcinoma with X-rays, although possible, has now been abandoned because of the danger of inducing ray damage to healthy boundary cells, which could trigger the emergence of a new radio-induced tumor.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Treatment_with_topical_pharmaceuticals\"><\/span><b>Treatment with topical pharmaceuticals<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Photodynamic_therapy_PDT_protocols_for_basal_cell_carcinoma\"><\/span>Photodynamic therapy (PDT): protocols for basal cell carcinoma<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>The protocol for ALA-PDT treatment of basal cell carcinoma involves many variations depending on tumor type, site, skin type, duration of injury, etc. The most common variations are the time of exposure to ALA and the number of PDT sessions to be scheduled.<\/p>\n<ol>\n<li>Examination, photographic documentation, additional investigations<\/li>\n<li>Patient information valid for obtaining informed consent<\/li>\n<li>Preparation of the lesion for PDT when necessary<\/li>\n<li>Application of 10% ALA with a suitable applicator<\/li>\n<li>Occlusion of the treated part with polyethylene film (or similar) to enhance penetration of the product<\/li>\n<li>Covering the treated area to prevent light penetration<\/li>\n<li>Waiting for development of protoporphyrin IX from between two to four hours, as indicated<\/li>\n<li>After the determined time has elapsed, removal of the dressing<\/li>\n<li>Observation of fluorescence with wood lamp as an index of protoporphyrin IX development<\/li>\n<li>Exposure of the ALA-treated area to red light for the amount of time it takes for the fluorescence to disappear (in the range of ten minutes, varying according to the light source)<\/li>\n<li>Upon completion, dressing of the treated area with <a href=\"https:\/\/mostskincare.com\/negozio\/linea-prodotti-dermatologica\/peg-unguento-2\/\" target=\"_blank\" rel=\"noopener\"><strong>PEG Ointment<\/strong><\/a> and cotton gauze<\/li>\n<li>At home, continuation of dressing with PEG Ointment once daily for a week<\/li>\n<li>After 30 days, if requested by the dermatologist, a second PDT session in the same manner as above may be performed<\/li>\n<li>Clinical follow-ups can be scheduled for three, six and\/or twelve months after<\/li>\n<li>In case of tumor recurrence, new PDT sessions can be scheduled or another treatment route can be investigated<\/li>\n<\/ol>\n<p>Results in the treatment of basal cell carcinoma with ALA-PDT<br \/>\nAccording to data from international studies, the success rate from treating basal cell carcinoma with ALA-PDT matches that which can be obtained with traditional surgery, and surpasses that which can be obtained with destructive methods (laser therapy, cryotherapy, radiofrequency, etc.). The strengths of ALA-PDT treatment are:<\/p>\n<ol>\n<li>No scarring and better cosmetic result<\/li>\n<li>No anesthetic<\/li>\n<li>No damage to healthy tissue surrounding the lesion<\/li>\n<li>Able to treat multiple lesions at the same time<\/li>\n<li>Able to treat extensive lesions or those not suitable for surgery<\/li>\n<li>Suitable for individuals who have not been cleared for surgery<\/li>\n<\/ol>\n<p>For these reasons, ALA-PDT treatment is considered as a therapy for basal cell carcinoma and should be offered to patients with this type of skin cancer.[\/vc_column_text][vc_column_text]<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Treatment_with_topical_pharmaceuticals-2\"><\/span><b>Treatment with topical pharmaceuticals<\/b><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>[\/vc_column_text][vc_column_text]The drug 5-fluorouracil (5-FU) is a chemotherapeutic that blocks cell reduplication and has been used in creams to treat basal cell carcinoma. However, the drug&#8217;s poor manageability and frequent tumor recurrences have limited its use.<br \/>\nThe drug imiquimod (an immunomodulator) in cream has also been used to treat these tumors but skin irritation, long healing time, frequent recurrences, and high cost have limited its use. <br \/>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Examples_of_PDT_treatment\"><\/span><b>Examples of PDT treatment<\/b><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;438&#8243; alignment=&#8221;center&#8221;][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;439&#8243; alignment=&#8221;center&#8221;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text]Basal cell carcinoma (previously basal cell epithelioma) is the most common cancer for humans. There are an estimated 150,000 new cases each year in Italy, while<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":2572,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[52],"tags":[56],"class_list":["post-3337","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-skin-diseases","tag-basal-cell-carcinoma"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.1 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Skin cancer induced by sun exposure or UV lamps<\/title>\n<meta name=\"description\" content=\"It is the most common cancer in humans and is caused by UV rays. 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